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Proceedings Paper

Application of thermoacoustic computed tomography to breast imaging
Author(s): Robert A. Kruger; William L. Kiser; Daniel R. Reinecke; Gabe A. Kruger
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Paper Abstract

Acoustic pressure waves are induced in soft tissue whenever time-varying radiation is absorbed. By recording these time- dependent pressure waves over a sufficient number of angles surrounding the tissue being imaged, it is possible to reconstruct the pattern of radiation absorption within the tissue in three dimensions with spatial resolution that is independent of the carrier frequency of the irradiating energy. We recently constructed the world's first thermoacoustic computed tomography (TACT) scanner, which exploits this physical interaction. Initial in vivo imaging of a human breast was performed using safe levels of 434 MHz radiation. Good soft tissue differentiation with 2 - 5 mm spatial resolution to a depth of 40 mm was achieved. The absorption properties of the breast and the irradiation pattern within the breast determined the TACT image contrast. The length of the RF pulse, the size of the transducers and their frequency response, the geometry of the detector array, and the reconstruction algorithm that was used determined the spatial resolution. We conclude that TACT imaging may have application to breast cancer detection.

Paper Details

Date Published: 28 May 1999
PDF: 5 pages
Proc. SPIE 3659, Medical Imaging 1999: Physics of Medical Imaging, (28 May 1999); doi: 10.1117/12.349519
Show Author Affiliations
Robert A. Kruger, Indiana Univ. Medical Ctr. and OptoSonics, Inc. (United States)
William L. Kiser, Indiana Univ. Medical Ctr. (United States)
Daniel R. Reinecke, OptoSonics, Inc. (United States)
Gabe A. Kruger, OptoSonics, Inc. (United States)

Published in SPIE Proceedings Vol. 3659:
Medical Imaging 1999: Physics of Medical Imaging
John M. Boone; James T. Dobbins, Editor(s)

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