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Proceedings Paper

Interactive MR image guidance for neurosurgical and minimally invasive procedures
Author(s): Terence Z. Wong; Richard B. Schwartz; Richard S. Pergolizzi; Peter McLaren Black; Daniel F. Kacher; Paul R. Morrison; Ferenc A. Jolesz
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Paper Abstract

Advantages of MR imaging for guidance of minimally invasive procedures include exceptional soft tissue contrast, intrinsic multiplanar imaging capability, and absence of exposure to ionizing radiation. Specialized imaging sequences are available and under development which can further enhance diagnosis and therapy. Flow-sensitive imaging techniques can be used to identify vascular structures. Temperature-sensitive imaging is possible which can provide interactive feedback prior to, during, and following the delivery of thermal energy. Functional MR imaging and dynamic contrast-enhanced MRI sequences can provide additional information for guidance in neurosurgical applications. Functional MR allows mapping of eloquent areas in the brain, so that these areas may be avoided during therapy. Dynamic contrast enhancement techniques can be useful for distinguishing active tumor from tumor necrosis caused by previous radiation therapy. An open-configuration 0.5T MRI system (GE Signa SP) developed at Brigham and Women's Hospital in collaboration with General Electric Medical Systems is described. Interactive navigation systems have been integrated into the MRI system. The imaging system is sited in an operating room environment, and used for image guided neurosurgical procedures (biopsies and tumor excision), as well as minimally invasive thermal therapies. Examples of MR imaging guidance, navigational techniques, and clinical applications are presented.

Paper Details

Date Published: 19 May 1999
PDF: 8 pages
Proc. SPIE 3594, Thermal Treatment of Tissue with Image Guidance, (19 May 1999); doi: 10.1117/12.348735
Show Author Affiliations
Terence Z. Wong, Duke Univ. Medical Ctr. and Brigham and Women's Hospital (United States)
Richard B. Schwartz, Brigham and Women's Hospital/Harvard Medical School (United States)
Richard S. Pergolizzi, Brigham and Women's Hospital/Harvard Medical School (United States)
Peter McLaren Black, Brigham and Women's Hospital/Harvard Medical School (United States)
Daniel F. Kacher, Brigham and Women's Hospital/Harvard Medical School (United States)
Paul R. Morrison, Harvard Medical School (United States)
Ferenc A. Jolesz, Brigham and Women's Hospital/Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 3594:
Thermal Treatment of Tissue with Image Guidance
Thomas P. Ryan; Terence Z. Wong, Editor(s)

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