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Proceedings Paper

Description of an improved laser Doppler calibrator
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Paper Abstract

An improved version of our laser Doppler tester has been developed. The tester contains a tissue phantom made in the form of a thin film. Films with a thickness in the range 20 - 90 micrometer are stacked to reach a total thickness of several millimeters. Motion is realized by rotating discs with a thickness of 20 - 22 micrometer, separated by a static layer of 95 micrometer thickness. The total number of movable layers is 13. The tester contains four phantom stacks, each mimicking a different type of tissue. Since each tissue consists of a stack of thin layers separated by a matching medium, the consequence of a possible mismatch on the photon penetration depth is investigated with the Monte Carlo simulation technique. This leads to a range of refractive indices in which the matching medium must be taken to keep the effect of mismatch below an acceptable level. It appears that for a tissue structure composed of layers with a thickness of 30 micrometer, the refractive index of the matching material should be between 1.50 and 1.54 for a refractive index of the matrix material of the phantom equal to 1.52. Within this range, the effect of mismatch on the probed depth and the total reflection is limited to 2%.

Paper Details

Date Published: 17 May 1999
PDF: 8 pages
Proc. SPIE 3599, Optical Diagnostics of Biological Fluids IV, (17 May 1999); doi: 10.1117/12.348364
Show Author Affiliations
Wiendelt Steenbergen, Univ. of Twente (Netherlands)
Frits F. M. de Mul, Univ. of Twente (Netherlands)


Published in SPIE Proceedings Vol. 3599:
Optical Diagnostics of Biological Fluids IV
Alexander V. Priezzhev; Toshimitsu Asakura, Editor(s)

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