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Proceedings Paper

Laser desorption mass spectrometry for high-throughput DNA analysis and its applications
Author(s): C. H. Winston Chen; Valeri V. Golovlev; N. I. Taranenko; S. L. Allman; Narayana R. Isola; N. T. Potter; K. J. Matteson; Linus Y.Y. Chang
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Paper Abstract

Laser desorption mass spectrometry (LDMS) has been developed for DNA sequencing, disease diagnosis, and DNA fingerprinting for forensic applications. With LDMS, the speed of DNA analysis can be much faster than conventional gel electrophoresis. No dye or radioactive tagging to DNA segments for detection is needed. LDMS is emerging as a new alternative technology for DNA analysis.

Paper Details

Date Published: 3 May 1999
PDF: 8 pages
Proc. SPIE 3602, Advances in Fluorescence Sensing Technology IV, (3 May 1999); doi: 10.1117/12.347532
Show Author Affiliations
C. H. Winston Chen, Oak Ridge National Lab. (United States)
Valeri V. Golovlev, Oak Ridge Associated Universities (United States)
N. I. Taranenko, Oak Ridge Associated Universities (United States)
S. L. Allman, Oak Ridge National Lab. (United States)
Narayana R. Isola, Oak Ridge Associated Universities (United States)
N. T. Potter, Univ. of Tennessee Medical Ctr./Knoxville (United States)
K. J. Matteson, Univ. of Tennessee Medical Ctr./Knoxville (United States)
Linus Y.Y. Chang, Chinese Academia Sinica (Taiwan)


Published in SPIE Proceedings Vol. 3602:
Advances in Fluorescence Sensing Technology IV
Joseph R. Lakowicz; Steven A. Soper; Richard B. Thompson, Editor(s)

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