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Proceedings Paper

Minimization of artifacts due to surface effects in laser CT images reconstructed by FBP method
Author(s): Yuuki Watanabe; Tetsuya Yuasa; Balasigamani Devaraj; Takao Akatsuka; Humio Inaba
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Paper Abstract

Optical tomography for biomedical target is an evolving research area with emerging potential applications. In transillumination optical tomography, the filtered back projection (FBP) method is generally used for image reconstruction and the images represent a distribution of the optical attenuation coefficient. However, in practical optical imaging systems, refractive index mismatch at boundaries, such as the tissue surface, strongly affects optical attenuation. The surface effects are not constant even at the same part of the sample at different incident angles. Therefore, the surface effects introduce artifacts that obscure the internal structure and functional information in the laser CT images reconstructed by the FBP method. In this paper, we propose a simple correction method that could minimize the surface effects in laser CT images. The experiments were performed with the coherent detection imaging system based on the optical heterodyne detection technique. Experimentally determined attenuation coefficient corresponding to different incident angles was used to correct the surface effects. Improved target structures were demonstrated in the reconstructed laser CT images. Our correction method for laser CT image reconstruction is quite effective for visualizing internal structures with small variations in attenuation coefficients that would otherwise be masked by the dominant surface attenuation.

Paper Details

Date Published: 30 April 1999
PDF: 8 pages
Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); doi: 10.1117/12.347481
Show Author Affiliations
Yuuki Watanabe, Yamagata Univ. (Japan)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Balasigamani Devaraj, Biophotonics Information Labs. (United States)
Takao Akatsuka, Yamagata Univ. (Japan)
Humio Inaba, Biophotonics Information Labs. and Tohoku Institute of Technology (Japan)

Published in SPIE Proceedings Vol. 3598:
Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III
Valery V. Tuchin; Joseph A. Izatt, Editor(s)

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