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Proceedings Paper

Refractive index matching of tissue components as a new technology for correlation and diffusing-photon spectroscopy and imaging
Author(s): Valery V. Tuchin; Joseph P. Culver; Cecil Cheung; Svetlana A. Tatarkova; Michael A. DellaVecchia M.D.; Dmitry A. Zimnyakov; Anatoly A. Chaussky; Arjun G. Yodh; Britton Chance
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Paper Abstract

The refractive index matching of components of highly scattering tissue has a strong influence on its transmittance and reflectance what can be considered as a new tool for imaging within relatively thick tissues. We present experimental data on various solutions, gels and oils influence on optical properties of in vivo human eye and in vivo human skin. The dynamics of tissue optical properties depending on matter diffusion rate within tissue is studied. The possible application of refractive index matching effect for diffusing-photon imaging is discussed.

Paper Details

Date Published: 30 April 1999
PDF: 10 pages
Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); doi: 10.1117/12.347479
Show Author Affiliations
Valery V. Tuchin, Saratov State Univ. (Russia)
Joseph P. Culver, Univ. of Pennsylvania (United States)
Cecil Cheung, Univ. of Pennsylvania (United States)
Svetlana A. Tatarkova, Saratov State Univ. (Russia)
Michael A. DellaVecchia M.D., Wills Eye Hospital (United States)
Dmitry A. Zimnyakov, Saratov State Univ. (Russia)
Anatoly A. Chaussky, Saratov State Univ. (Russia)
Arjun G. Yodh, Univ. of Pennsylvania (United States)
Britton Chance, Univ. of Pennsylvania (United States)

Published in SPIE Proceedings Vol. 3598:
Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III
Valery V. Tuchin; Joseph A. Izatt, Editor(s)

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