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Proceedings Paper

Determination of burn depth by polarization-sensitive optical coherence tomography
Author(s): Shyam M. Srinivas; Johannes F. de Boer; Boris Hyle Park; Kurosh Keikhanzadeh; Leah Huang; Zhongping Chen; J. Stuart Nelson
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Paper Abstract

Burn depth assessment is a key step guiding the treatment plan in patients who have sustained thermal injuries. We have developed a technique, polarization sensitive optical coherence tomography (PS-OCT), to provide the physician with a quantitative estimate of actual burn depth. We generated burns of various depths by contacting rates with a brass rod preheated to 75 degrees for 5, 15, or 30 seconds. PS-OCT imags birefringence in biological tissue, through the depth resolved changes in the polarization state of light propagated and reflected from the sample. Preliminary result are presented that show a correlation between the loss of birefringence due to thermal injury and the actual burn depth determined by histological analysis. PS-OCT is a noninvasive technique which potentially can give physicians the accuracy to formulate the best treatment plan for burn patients.

Paper Details

Date Published: 30 April 1999
PDF: 9 pages
Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); doi: 10.1117/12.347475
Show Author Affiliations
Shyam M. Srinivas, Beckman Laser Institute and Medical Clinic (United States)
Johannes F. de Boer, Beckman Laser Institute and Medical Clinic (United States)
Boris Hyle Park, Beckman Laser Institute and Medical Clinic (United States)
Kurosh Keikhanzadeh, Beckman Laser Institute and Medical Clinic (United States)
Leah Huang, Beckman Laser Institute and Medical Clinic (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)
J. Stuart Nelson, Beckman Laser Institute and Medical Clinic (United States)


Published in SPIE Proceedings Vol. 3598:
Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III
Valery V. Tuchin; Joseph A. Izatt, Editor(s)

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