Share Email Print
cover

Proceedings Paper

Observation of DNA fixed on a sapphire substrate by a collection mode near-field optical microscope
Author(s): Uma Maheswari Rajagopalan; Shuji Mononobe; Kenji Yoshida; Mamoru Yoshimoto; Motoichi Ohtsu
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We present the observation results of a single string DNA (deoxy ribo nucleic acid) obtained by collection mode near- field optical microscopy operated under constant distance mode with the optical near field intensity as the feedback signal. The observed width of the narrowest string is 4 nm. To our knowledge, this is not only the successful optical observation of a single string DNA by purely optical means but also under such high resolving capability. These are attributed to the special care taken during the sample preparation to avoid unwanted scattered light and to the probe which were specially designed to enhance the local near field interaction. All these factors make the probe picks up efficiently the high spatial frequency components of the scattered near field at the same time rejecting effectively the lower spatial frequency components.

Paper Details

Date Published: 29 April 1999
PDF: 6 pages
Proc. SPIE 3729, Selected Papers from International Conference on Optics and Optoelectronics '98, (29 April 1999); doi: 10.1117/12.346822
Show Author Affiliations
Uma Maheswari Rajagopalan, Kanagawa Academy of Science and Technology (Japan)
Shuji Mononobe, Kanagawa Academy of Science and Technology (Japan)
Kenji Yoshida, Tokyo Institute of Technology (Japan)
Mamoru Yoshimoto, Tokyo Institute of Technology (Japan)
Motoichi Ohtsu, Kanagawa Academy of Science and Technology and Tokyo Institute of Technology (Japan)


Published in SPIE Proceedings Vol. 3729:
Selected Papers from International Conference on Optics and Optoelectronics '98
Kehar Singh; Om Prakash Nijhawan; Arun Kumar Gupta; A. K. Musla, Editor(s)

© SPIE. Terms of Use
Back to Top