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Proceedings Paper

96-channel microplate surface plasmon resonance fiber optic sensor system
Author(s): Ralph C. Jorgenson; Mark C. Siegfried
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Paper Abstract

A surface plasmon resonance fiber optic system is presented for the simultaneous analysis of ninety-six micro-well plates for purposes of high throughput biochemical screening analysis. The sensing element is compared of ninety-six discrete fiber optic sensor housed in a containment plate. A white light source is used to introduce light to the sensor via a multiplexed fiber optic bundle. The transmitted spectral intensity distribution of each sensor is detected via a multiplexed fiber optic bundle. The transmitted spectral intensity distribution of each sensor is detected simultaneously using a lens-based holographic imaging spectrograph and a 2D CCD detector. Experimental results confirm the feasibility of the application of this label free and real-time transduction mechanism of surface plasmon resonance towards high throughput biochemical analysis.

Paper Details

Date Published: 21 April 1999
PDF: 10 pages
Proc. SPIE 3603, Systems and Technologies for Clinical Diagnostics and Drug Discovery II, (21 April 1999); doi: 10.1117/12.346756
Show Author Affiliations
Ralph C. Jorgenson, EBI Sensors, Inc. (United States)
Mark C. Siegfried, EBI Sensors, Inc. (United States)


Published in SPIE Proceedings Vol. 3603:
Systems and Technologies for Clinical Diagnostics and Drug Discovery II
Gerald E. Cohn; John C. Owicki, Editor(s)

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