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Proceedings Paper

Modeling of functional brain imaging data
Author(s): Barry Horwitz
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Paper Abstract

The richness and complexity of data sets obtained from functional neuroimaging studies of human cognitive behavior, using techniques such as positron emission tomography and functional magnetic resonance imaging, have until recently not been exploited by computational neural modeling methods. In this article, following a brief introduction to functional neuroimaging methodology, two neural modeling approaches for use with functional brain imaging data are described. One, which uses structural equation modeling, examines the effective functional connections between various brain regions during specific cognitive tasks. The second employs large-scale neural modeling to relate functional neuroimaging signals in multiple, interconnected brain regions to the underlying neurobiological time-varying activities in each region. These two modeling procedures are illustrated using a visual processing paradigm.

Paper Details

Date Published: 22 March 1999
PDF: 10 pages
Proc. SPIE 3728, Ninth Workshop on Virtual Intelligence/Dynamic Neural Networks, (22 March 1999); doi: 10.1117/12.343050
Show Author Affiliations
Barry Horwitz, National Institute on Aging (United States)


Published in SPIE Proceedings Vol. 3728:
Ninth Workshop on Virtual Intelligence/Dynamic Neural Networks
Thomas Lindblad; Mary Lou Padgett; Jason M. Kinser, Editor(s)

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