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Proceedings Paper

Ischemic and bleeding disease monitoring with fNIRS imager: one case report
Author(s): Weiguo Chen; Pengcheng Li; Shaoqun Zeng; Qingming Luo; Zhi Zhang; Hui Gong; Britton Chance
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Paper Abstract

We detected oxyhemoglobin (HbO2) content change and blood volume of the bleeding model in vivo with NIRS imager. The results showed that the minimum detect limit of NIRS imager is 0.5 ml and the optimum detect depth is 2 - 5 cm under skin. In our test, the imager could detect small change of the blood volume easily, but the HbO2 content in hyperemia location hadn't obvious change. The results suggested that injected blood was venous blood which had lower HbO2 content level. In single channel blood oxygen test, we observed that deoxyhemoglobin, blood volume had significant changes after 0.5 ml venous blood was injected each time. But the oxyhemoglobin hadn't obvious change too. The NIRS imager could determine the location, range and depth of ischemia or bleeding diseases. Because the instrument is cheap, portable, and operate easily, it is promising in family diagnosis and sport medicine.

Paper Details

Date Published: 4 March 1999
PDF: 5 pages
Proc. SPIE 3726, Saratov Fall Meeting '98: Light Scattering Technologies for Mechanics, Biomedicine, and Material Science, (4 March 1999); doi: 10.1117/12.341439
Show Author Affiliations
Weiguo Chen, Huazhong Univ. of Science and Technology (China)
Pengcheng Li, Huazhong Univ. of Science and Technology (China)
Shaoqun Zeng, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)
Zhi Zhang, Huazhong Univ. of Science and Technology (China)
Hui Gong, Huazhong Univ. of Science and Technology (China)
Britton Chance, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 3726:
Saratov Fall Meeting '98: Light Scattering Technologies for Mechanics, Biomedicine, and Material Science
Valery V. Tuchin; Vladimir P. Ryabukho; Dmitry A. Zimnyakov, Editor(s)

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