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Proceedings Paper

Multichannel arrays on polymer substrates: toward a disposable proteomics chip
Author(s): Holger Becker; Wolfgang Ehrfeld; Rainer Pommersheim
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Paper Abstract

Miniaturization is dramatically changing the shape of biotechnology. After the first wave of discoveries inventions in the field of analytical methods and DNA-probes on silicon chips, the trend in recent years has been to more complex and integrated systems in terms of microfabrication for production purposes mainly focused on polymer substrates. Additionally, an increased complexity in the biochemical functionality for tasks like cell handling, cell lysis, polymerase chain reaction, DNA-sequencing and recently in the field of proteomics research can be observed. In this paper we describe the practical approach to a polymer substrate based, microfabricated chip-based multichannel array for 2D capillary electrophoresis. This chip can be fabricated by classical mass production techniques like hot embossing or injection modeling, and has the potential for on-chip-integration of electrodes and detection system.

Paper Details

Date Published: 10 March 1999
PDF: 6 pages
Proc. SPIE 3680, Design, Test, and Microfabrication of MEMS and MOEMS, (10 March 1999); doi: 10.1117/12.341266
Show Author Affiliations
Holger Becker, Jenoptik Mikrotechnik GmbH (Germany)
Wolfgang Ehrfeld, Institut fuer Mikrotechnik Mainz GmbH (Germany)
Rainer Pommersheim, Institut fuer Mikrotechnik Mainz GmbH (Germany)

Published in SPIE Proceedings Vol. 3680:
Design, Test, and Microfabrication of MEMS and MOEMS
Bernard Courtois; Wolfgang Ehrfeld; Selden B. Crary; Wolfgang Ehrfeld; Hiroyuki Fujita; Jean Michel Karam; Karen W. Markus, Editor(s)

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