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Proceedings Paper

Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study
Author(s): Nicolas Bocquillon; Serge R. Mordon; D. Mathieu; Vincent Maunoury; Xavier-Marie Marechal; Remi Neviere; Francis Wattel; Claude Chopin
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Paper Abstract

Microcirculatory disorders of the gastrointestinal tract appear to be a major compound of the multiple organ dysfunction syndrome secondary to sepsis or septic shock. A better analysis of mucosal hypoperfusion in critically ill patients with sepsis may be helpful for the comprehension of this high mortality-associated syndrome. Fluorescence endoscopy has been recognized as a non-invasive method for both spatial and temporal evaluation of gastrointestinal mucosal perfusion. We performed this imaging technique during routine gastric endoscopy in patients with sepsis criteria. The study included gastric observation and appearance time of gastric fluorescence after an intravenous 10% sodium - fluorescein bolus. Qualitative analysis of high fluorescence areas was compared with mucosal blood flow measurements by laser - Doppler flowmetry. We concluded that the fluorescence endoscopic imaging in critically ill patients with sepsis may reveal spacial and temporal differences in the mucosal microcirculation distribution.

Paper Details

Date Published: 12 February 1999
PDF: 9 pages
Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); doi: 10.1117/12.339193
Show Author Affiliations
Nicolas Bocquillon, Hopital Calmette/CHRU de Lille and INSERM (France)
Serge R. Mordon, INSERM (France)
D. Mathieu, Hopital Calmette/CHRU de Lille and INSERM (France)
Vincent Maunoury, Hopital Huriez/CHRU de Lille (France)
Xavier-Marie Marechal, INSERM (Japan)
Remi Neviere, Hopital Calmette/CHRU de Lille and INSERM (France)
Francis Wattel, Hopital Calmette/CHRU de Lille (France)
Claude Chopin, INSERM (France)

Published in SPIE Proceedings Vol. 3567:
Optical and Imaging Techniques for Biomonitoring IV
Marco Dal Fante; Hans-Jochen Foth; Neville Krasner; Renato Marchesini; Halina Podbielska, Editor(s)

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