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Proceedings Paper

Asymmetry of light backscattering from Couette flow of RBC suspensions: application for biomonitoring of blood samples
Author(s): Alexander V. Priezzhev; Stanislav G. Khatsevich; Vladimir V. Lopatin
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Paper Abstract

Asymmetry of light backscattering from a shear flow of 1 mm thick layer of whole blood was measured. The blood samples from different health and diseased individuals were placed in a gap of a cylindrical Couette cell with inner cylinder rotating with variable rates. Probing was performed with a CW He-Ne laser (633 nm). The difference in intensities of backscattered light detected through a transpatent wall of the stationary outer cylinder with a photodetector located at variable distances from the illuminating beam along and opposite to the flow directions depends on the distance between the illuminating and detecting probes, on shear rate, on hematocrit, and on the type of disease. The experiments conducted with blood samples from patients suffering from heart disease, bronchial asthma, and rheumatoid arthritis showed stable and reproducible difference in the amount of asymmetry. This makes the technique potentially applicable for optical biomonitoring and, also, for the study of rheology of concentrated suspensions of large deformable particles, like erythrocytes.

Paper Details

Date Published: 12 February 1999
PDF: 10 pages
Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); doi: 10.1117/12.339187
Show Author Affiliations
Alexander V. Priezzhev, M.V. Lomonosov Moscow State Univ. (Russia)
Stanislav G. Khatsevich, M.V. Lomonosov Moscow State Univ. (Russia)
Vladimir V. Lopatin, M.V. Lomonosov Moscow State Univ. (Russia)

Published in SPIE Proceedings Vol. 3567:
Optical and Imaging Techniques for Biomonitoring IV
Marco Dal Fante; Hans-Jochen Foth; Neville Krasner; Renato Marchesini; Halina Podbielska, Editor(s)

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