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Proceedings Paper

Aluminium sulphophthalocyanine as an NIR photosensitizer for PDT
Author(s): Boris Ya. Kogan; Alexander V. Butenin; Nadezgda L. Torshina; Eugenia A. Kogan; Oleg L. Kaliya; Eugeny A. Lukyanets; Yu. M. Luzhkov; Valentina M. Derkacheva; A. A. Pankratov; Georgy N. Vorozhtsov; Anna I. Volkova
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Paper Abstract

It was found that irradiation of aqueous solution of aluminum sulphophthalocyanine (SnPcAl) by light with wavelength of 805 nm in the presence of sodium ascorbate results in photodynamic type I effect. S2PcAl in adsorbed state on proteins or polysaccharide structures was shown to possess rather intense long wavelength absorption band in the NIR spectral region. The comparative tests of SnPcAl with sodium ascorbate on mice with Ehrlich carcinoma and leucosis P-388 showed that photodynamic efficiency in the case of NIR irradiation (790 nm) is not lower than using visible irradiation (675 nm).

Paper Details

Date Published: 3 February 1999
PDF: 4 pages
Proc. SPIE 3563, Photochemotherapy of Cancer and Other Diseases, (3 February 1999); doi: 10.1117/12.339131
Show Author Affiliations
Boris Ya. Kogan, State Scientific Ctr. NIOPIK (Russia)
Alexander V. Butenin, Organic Intermediates and Dyes Institute (Russia)
Nadezgda L. Torshina, General Physics Institute (Russia)
Eugenia A. Kogan, Sechenov Moscow Medical Academy (Russia)
Oleg L. Kaliya, Organic Intermediates and Dyes Institute (Russia)
Eugeny A. Lukyanets, Organic Intermediates and Dyes Institute (Russia)
Yu. M. Luzhkov, Organic Intermediates and Dyes Institute (Russia)
Valentina M. Derkacheva, Organic Intermediates and Dyes Institute (Russia)
A. A. Pankratov, Organic Intermediates and Dyes Institute (Russia)
Georgy N. Vorozhtsov, Organic Intermediates and Dyes Institute (Russia)
Anna I. Volkova, General Physics Institute (Russia)


Published in SPIE Proceedings Vol. 3563:
Photochemotherapy of Cancer and Other Diseases
Benjamin Ehrenberg; Kristian Berg, Editor(s)

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