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Proceedings Paper

Noninvasive determination of the optical properties of two-layered turbid media from time-resolved reflectance measurements
Author(s): Alwin Kienle; Thomas M. Glanzmann; Georges A. Wagnieres; Hubert van den Bergh
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Paper Abstract

The influence of the adipose tissue thickness on near- infrared spectroscopy to monitor the hemodynamics in muscles in investigated. It is shown by calculation of the mean optical pathlength of two-layered turbid media that the validity of the modified Beer-Lambert law is reduced with increasing thickness of the first layer (fat), because the assumption, that the mean optical pathlength is constant, is not fulfilled. In order to avoid these problems we demonstrate that it is possible to derive the optical properties of both layers from time-resolved reflectance measurements using a solution of the two-layered diffusion equation if the thickness of the first layer is known.

Paper Details

Date Published: 15 January 1999
PDF: 8 pages
Proc. SPIE 3570, Biomedical Sensors, Fibers, and Optical Delivery Systems, (15 January 1999); doi: 10.1117/12.336945
Show Author Affiliations
Alwin Kienle, Univ. of Ulm and Swiss Federal Institute of Technology (Germany)
Thomas M. Glanzmann, Swiss Federal Institute of Technology (Switzerland)
Georges A. Wagnieres, Swiss Federal Institute of Technology (Switzerland)
Hubert van den Bergh, Swiss Federal Institute of Technology (Switzerland)


Published in SPIE Proceedings Vol. 3570:
Biomedical Sensors, Fibers, and Optical Delivery Systems
Francesco Baldini; Nathan I. Croitoru; Martin Frenz; Ingemar Lundstroem; Mitsunobu Miyagi; Riccardo Pratesi; Otto S. Wolfbeis, Editor(s)

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