Share Email Print
cover

Proceedings Paper

Can tumor cell suspension serve as an optical model of tumor tissue in situ?
Author(s): Anna N. Yaroslavsky; Anja Vervoorts; Alexander V. Priezzhev; Ilya V. Yaroslavsky; Joerg G. Moser; Hans-Joachim Schwarzmaier
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We determined and compared to the optical properties of five samples obtained from xenotransplanted chick embryos chorio- allantoic membrane tumors, five samples obtained from xenotransplanted chick embryos yolk sac membrane tumors, and five samples of concentrated tumor cells suspension (small cell lung carcinoma OAT 75). The absorption coefficient (mu) a, the scattering coefficient (mu) s, the anisotropy factor g, and the reduced scattering coefficient (mu) s' were evaluated in the spectral range from 600 nm to 900 nm with a step width of 10 nm from double integrating sphere measurements using an inverse Monte Carlo technique. The results have shown that the optical properties of the concentrated tumor cell suspension are similar to those of the chorio-allantoic membrane tumor, but are essentially different from the optical properties of the yolk sac membrane tumor. Cell vitality tests have shown that the cells were alive during and after the experiments. Therefore, the tumor cell suspension can serve as an optical model of the chorio-allantoic membrane tumor in situ for testing and developing novel diagnostic and therapeutic techniques.

Paper Details

Date Published: 4 January 1999
PDF: 9 pages
Proc. SPIE 3565, Thermal Therapy, Laser Welding, and Tissue Interaction, (4 January 1999); doi: 10.1117/12.335799
Show Author Affiliations
Anna N. Yaroslavsky, Institut fuer Lasermedizin/Heinrich-Heine-Univ. (United States)
Anja Vervoorts, Institut fuer Lasermedizin/Heinrich-Heine-Univ. (Germany)
Alexander V. Priezzhev, Moscow State Univ. (Russia)
Ilya V. Yaroslavsky, Institut fuer Lasermedizin/Heinrich-Heine-Univ. (United States)
Joerg G. Moser, Institut fuer Lasermedizin/Heinrich-Heine-Univ. (Germany)
Hans-Joachim Schwarzmaier, German National Research Ctr. for Information Technology (Germany)


Published in SPIE Proceedings Vol. 3565:
Thermal Therapy, Laser Welding, and Tissue Interaction
Stephen G. Bown; Guy P. Delacretaz; Guilhem Godlewski; Gerhard J. Mueller; Roberto Pini; Hans-Dieter Reidenbach; Rudolf W. Steiner; Lars Othar Svaasand; Karl-Goran Tranberg, Editor(s)

© SPIE. Terms of Use
Back to Top