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Proceedings Paper

Master oscillator power amplifier diode laser and microarterial anastomosis with chromophore
Author(s): Francois-Marie Lhote; Roland G. Demaria; Simone Rouy; Michel Dauzat; Marie-Claire Lauraire; Romain Roduit; Michel Prudhomme; Guy P. Delacretaz; Guilhem Godlewski
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Paper Abstract

Feasibility of laser assisted micro-vascular anastomosis (LAMA) has already been proved for more than 15 years. But to our knowledge, equivalence between LAMA and conventional manual anastomosis (CMA) has never been demonstrated. With a Master Oscillator Power Amplifier diode laser (988 nm) and Fast Green FCF as chromophore, LAMA versus CMA were performed on the carotids of 92 Wistar rats. LAMA edge coaptation was achieved with three 10/0 stitches, irradiation with 3 shots of 500 mW in power and 800 nm in diameter. CMA was performed on the other side with six 10/0 stitches. At 2 months, 3 aneurysms were present on LAMA side and 3 on CMA side, the success rate was 96.7% on both sides. We established the equivalence of LAMA and CMA, in an interval of 5%, using a method of equivalence based on odds ratios and Chi-square test. Paired t-test comparing carotid flow, maximal Doppler frequencies, pulsatility and resistance index could not highlight any difference between the 2 methods. Histological analysis showed an earlier and better re-endothelialization on LAMA side. For the first time to our knowledge equivalent between LAMA and CMA has been demonstrated.

Paper Details

Date Published: 4 January 1999
PDF: 5 pages
Proc. SPIE 3565, Thermal Therapy, Laser Welding, and Tissue Interaction, (4 January 1999); doi: 10.1117/12.335784
Show Author Affiliations
Francois-Marie Lhote, Univ. de Montpellier I (France)
Roland G. Demaria, Hopital Arnaud de Villeneuve (France)
Simone Rouy, Univ. de Montpellier I (France)
Michel Dauzat, Univ. de Montpellier I (France)
Marie-Claire Lauraire, Univ. de Montpellier I (France)
Romain Roduit, Ecole Polytechnique Federale de Lausanne (Switzerland)
Michel Prudhomme, Univ. de Montpellier I (France)
Guy P. Delacretaz, Ecole Polytechnique Federale de Lausanne (Switzerland)
Guilhem Godlewski, Univ. de Montpellier I (France)


Published in SPIE Proceedings Vol. 3565:
Thermal Therapy, Laser Welding, and Tissue Interaction
Stephen G. Bown; Guy P. Delacretaz; Guilhem Godlewski; Gerhard J. Mueller; Roberto Pini; Hans-Dieter Reidenbach; Rudolf W. Steiner; Lars Othar Svaasand; Karl-Goran Tranberg, Editor(s)

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