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Proceedings Paper

Effect of refractive index and calibration factor on image reconstruction in optical tomography
Author(s): Pieter van der Zee; Reem Khalaf; Laurence C. W. Dixon; Alan Davies
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Paper Abstract

Results obtained with an experimental Optical Tomography system, using a frequency domain technique and a cylindrical geometry are presented. In particular, problems occurring in the reconstruction of Optical Tomography images due to uncertainties in the values for relative refractive index and system calibration factor have been investigated. It is shown that considerable errors can arise in the values for the reconstructed absorption and diffusion images as a result of these uncertainties, and that these uncertainties can give rise to artifacts in the reconstructed images. In addition, the degeneracy between the absorption coefficient, (mu) a, and the diffusion coefficient, D, is shown for reconstruction from DC data, with the conclusion that for optimal reconstruction DC data cannot be discarded, and therefore an accurate system calibration remains a necessity.

Paper Details

Date Published: 30 December 1998
PDF: 8 pages
Proc. SPIE 3566, Photon Propagation in Tissues IV, (30 December 1998); doi: 10.1117/12.334373
Show Author Affiliations
Pieter van der Zee, Univ. of Hertfordshire (United Kingdom)
Reem Khalaf, Univ. of Hertfordshire (United Kingdom)
Laurence C. W. Dixon, Univ. of Hertfordshire (United Kingdom)
Alan Davies, Univ. of Hertfordshire (United Kingdom)

Published in SPIE Proceedings Vol. 3566:
Photon Propagation in Tissues IV
David A. Benaron; Britton Chance; Marco Ferrari; Matthias Kohl-Bareis, Editor(s)

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