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Proceedings Paper

Onco-hematological diagnostics by IR spectroscopy
Author(s): Sergey D. Darchuk; Larisa A. Korovina; Fiodor F. Sizov; Vladimir G. Bebeshko
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Paper Abstract

Application of the infrared (IR) spectroscopy to early medical onco-hematological diagnostics, in particular to leukemia, is described. Leukemia is characterized by the orthophosphates acid (soluble) forms (HPO42-) accumulation in bone apatites. Bone hydroxyapatite contains predominantly basic PO43- nonsoluble orthophosphate. At the same time condensed forms of pyrophosphates (e.g., CaH2P3O7) in bones and especially in dried urine were found by the analysis of IR absorption spectra of persons with leukemia. It was show that the dried urine infrared quantitative absorption spectra investigations of phosphates contents make it possible to trace the dynamics of these elements contents during the leukemia progression and can serve for onco-hematological diagnostics at early stage of leukemia.

Paper Details

Date Published: 26 October 1998
PDF: 7 pages
Proc. SPIE 3436, Infrared Technology and Applications XXIV, (26 October 1998); doi: 10.1117/12.327999
Show Author Affiliations
Sergey D. Darchuk, Institute of Semiconductor Physics (Ukraine)
Larisa A. Korovina, Ukrainian Ctr. of Radiation Medicine (Ukraine)
Fiodor F. Sizov, Institute of Semiconductor Physics (Ukraine)
Vladimir G. Bebeshko, Ukrainian Ctr. of Radiation Medicine (Ukraine)

Published in SPIE Proceedings Vol. 3436:
Infrared Technology and Applications XXIV
Bjorn F. Andresen; Marija Strojnik, Editor(s)

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