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Proceedings Paper

Development of a red diode laser system for photodynamic therapy
Author(s): Konstantinos N. Halkiotis; Dido M. Yova; Nikolaos K. Uzunoglou; Georgios Papastergiou; Sotiris Matakias; Ilias Koukouvinos
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Paper Abstract

The effectiveness of photodynamic treatment modality has been proven experimentally for a large variety of tumors, during the last years. This therapy utilizes the combined action of light and photosensitizing drug. Until now, a disadvantage of PDT has be the low tissue penetration of light, at the wavelengths of most commonly available lasers, for clinical studies. The red wavelength offers the advantage of increased penetration depth in tissue, in addition several new wavelength offers the advantage of increased penetration depth in tissue, in addition several new photosensitizers present absorption band at the region 630nm to 690nm. The development of high power red diode laser system for photodynamic therapy, has provided a cost effective alternative to existing lasers for use in PDT. This paper will describe the system design, development and performance of a diode laser system, connected with a fiber optic facility, to be used for PDT. The system was based on a high power semiconductor diode laser emitting at 655nm. The laser output power was approximately 60mW at the output of a 62.5/125/900 micron fiber optic probe. FUll technical details and optical performance characteristics of the system will be discussed in this paper.

Paper Details

Date Published: 14 July 1998
PDF: 6 pages
Proc. SPIE 3423, Second GR-I International Conference on New Laser Technologies and Applications, (14 July 1998); doi: 10.1117/12.316628
Show Author Affiliations
Konstantinos N. Halkiotis, National Technical Univ. of Athens (Greece)
Dido M. Yova, National Technical Univ. of Athens (Greece)
Nikolaos K. Uzunoglou, National Technical Univ. of Athens (Greece)
Georgios Papastergiou, Optronics EYT (Greece)
Sotiris Matakias, Optronics EYT (Greece)
Ilias Koukouvinos, Optronics EYT (Greece)


Published in SPIE Proceedings Vol. 3423:
Second GR-I International Conference on New Laser Technologies and Applications
Alexis Carabelas; Paolo Di Lazzaro; Amalia Torre; Giuseppe Baldacchini, Editor(s)

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