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Proceedings Paper

Assessment of dynamic magnetic resonance images using an independent workstation for determination, visualization, and quantitative analysis of pharmacokinetic and physiological parameters
Author(s): Roland Bammer; Markus Pedevilla; Stefan Ropele; Paul Wach; Franz Ebner; Rudolf Stollberger
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Paper Abstract

In addition to conventional MR parameters such as proton density and relaxation times T1 and T2, further specific parameters (magnetization transfer, apparent diffusion, temperature, blood oxygen level) have been observed by recent developments in Magnetic Resonance Imaging. When employing several approaches, such as indicator dilution theory or pharmacokinetic modeling, further valuable information can be derived from MR raw data sets. This additional information could give more insight into various clinical areas. It can be utilized to investigate hemodynamic perturbations and tumor- related pharmacokinetic features. Most of these techniques rely on a large amount of MR raw data. Hence, an efficient strategy for data organization and postprocessing and clear image data presentation is necessary for these techniques to be implemented as clinical routine work. A novel software concept has been developed to address all these issues. It is based on a more general framework of basic classes for data IO and manipulation, viewing and image processing. For a maximum of flexibility, the presented design separates data management and image presentation from dedicated MR analysis. It provides facilities for incorporation of user-defined routines and a comprehensive set of basic functions which enable rapid software prototyping.

Paper Details

Date Published: 3 July 1998
PDF: 11 pages
Proc. SPIE 3337, Medical Imaging 1998: Physiology and Function from Multidimensional Images, (3 July 1998); doi: 10.1117/12.312584
Show Author Affiliations
Roland Bammer, Karl-Franzens-Univ. of Graz School of Medicine (Austria)
Markus Pedevilla, Karl-Franzens-Univ. of Graz School of Medicine (Austria)
Stefan Ropele, Karl-Franzens-Univ. of Graz School of Medicine (Austria)
Paul Wach, Graz Univ. of Technology (Austria)
Franz Ebner, Karl-Franzens-Univ. of Graz School of Medicine (Austria)
Rudolf Stollberger, Karl-Franzens-Univ. of Graz School of Medicine (Austria)


Published in SPIE Proceedings Vol. 3337:
Medical Imaging 1998: Physiology and Function from Multidimensional Images
Eric A. Hoffman, Editor(s)

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