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Proceedings Paper

Critical temperature transitions in laser-mediated cartilage reshaping
Author(s): Brian Jet-Fei Wong; Thomas E. Milner; Hong H. Kim; Sergey A. Telenkov; Clifford Chew; Timothy C. Kuo; Derek J. Smithies; Emil N. Sobol; J. Stuart Nelson
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Paper Abstract

In this study, we attempted to determine the critical temperature [Tc] at which accelerated stress relaxation occurred during laser mediated cartilage reshaping. During laser irradiation, mechanically deformed cartilage tissue undergoes a temperature dependent phase transformation which results in accelerated stress relaxation. When a critical temperature is attained, cartilage becomes malleable and may be molded into complex new shapes that harden as the tissue cools. Clinically, reshaped cartilage tissue can be used to recreate the underlying cartilaginous framework of structures such as the ear, larynx, trachea, and nose. The principal advantages of using laser radiation for the generation of thermal energy in tissue are precise control of both the space-time temperature distribution and time- dependent thermal denaturation kinetics. Optimization of the reshaping process requires identification of the temperature dependence of this phase transformation and its relationship to observed changes in cartilage optical, mechanical, and thermodynamic properties. Light scattering, infrared radiometry, and modulated differential scanning calorimetry (MDSC) were used to measure temperature dependent changes in the biophysical properties of cartilage tissue during fast (laser mediated) and slow (conventional calorimetric) heating. Our studies using MDSC and laser probe techniques have identified changes in cartilage thermodynamic and optical properties suggestive of a phase transformation occurring near 60 degrees Celsius.

Paper Details

Date Published: 1 July 1998
PDF: 12 pages
Proc. SPIE 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII, (1 July 1998); doi: 10.1117/12.312284
Show Author Affiliations
Brian Jet-Fei Wong, Beckman Laser Institute and Medical Clinic and Univ. of California/Irvine School of Medici (United States)
Thomas E. Milner, Univ. of Texas/Austin (United States)
Hong H. Kim, Beckman Laser Institute and Medical Clinic (United States)
Sergey A. Telenkov, Beckman Laser Institute and Medical Clinic (United States)
Clifford Chew, Beckman Laser Institute and Medical Clinic and Univ. of California/Irvine School of Medici (United States)
Timothy C. Kuo, Beckman Laser Institute and Medical Clinic and Univ. of California/Irvine School of Medici (United States)
Derek J. Smithies, Beckman Laser Institute and Medical Clinic and Triton Commercial Systems Ltd. (United States)
Emil N. Sobol, Ctr. for Technological Lasers (Russia)
J. Stuart Nelson, Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 3245:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII
Graham M. Watson; Harvey Lui; Lou Reinisch; Penny J. Smalley; Kenneth Eugene Bartels; R. Rox Anderson; Lawrence S. Bass; Kenneth Eugene Bartels; C. Gaelyn Garrett; Lloyd P. Tate; Sharon L. Thomsen; Reza S. Malek; Aaron P. Perlmutter; R. Rox Anderson; Lawrence S. Bass; C. Gaelyn Garrett; Kenton W. Gregory; Harvey Lui; Reza S. Malek; Aaron P. Perlmutter; Lou Reinisch; Penny J. Smalley; Lloyd P. Tate; Sharon L. Thomsen; Graham M. Watson, Editor(s)

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