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Proceedings Paper

Synchronous luminescence spectroscopy of human breast tissues
Author(s): S. K. Majumdar; P. K. Gupta
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Paper Abstract

We report, to our knowledge, the first use of synchronous luminescence (SL) spectroscopy for autofluorescence diagnosis of cancer. The spectral narrowing effect of the SL spectroscopy led to an easier identification of the different fluorophores present in human breast tissues and provided relative estimate of their concentration in qualitative agreement with the estimates obtained from conventional excitation and emission spectroscopy. Further, the SL spectra from human breast tissues could discriminate cancerous tissues from benign tumors and normal tissues with a sensitivity and specificity of 100% in a study involving 34 patients with breast tumor (19 ductal carcinomas and 15 fibroadenomas).

Paper Details

Date Published: 19 June 1998
PDF: 10 pages
Proc. SPIE 3252, Optical Diagnostics of Biological Fluids III, (19 June 1998); doi: 10.1117/12.311885
Show Author Affiliations
S. K. Majumdar, Ctr. for Advanced Technology (India)
P. K. Gupta, Ctr. for Advanced Technology (India)

Published in SPIE Proceedings Vol. 3252:
Optical Diagnostics of Biological Fluids III
Alexander V. Priezzhev; Toshimitsu Asakura; J. David Briers, Editor(s)

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