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Proceedings Paper

Reproducibility of MRI segmentation using a feature space method
Author(s): Hamid Soltanian-Zadeh; Joe P. Windham; Lisa Scarpace; Tanya Murnock
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Paper Abstract

This paper presents reproducibility studies for the segmentation results obtained by our optimal MRI feature space method. The steps of the work accomplished are as follows. (1) Eleven patients with brain tumors were imaged by a 1.5 T General Electric Signa MRI System. Four T2- weighted and two T1-weighted images (before and after Gadolinium injection) were acquired for each patient. (2) Images of a slice through the center of the tumor were selected for processing. (3) Patient information was removed from the image headers and new names (unrecognizable by the image analysts) were given to the images. These images were blindly analyzed by the image analysts. (4) Segmentation results obtained by the two image analysts at two time points were compared to assess the reproducibility of the segmentation method. For each tissue segmented in each patient study, a comparison was done by kappa statistics and a similarity measure (an approximation of kappa statistics used by other researchers), to evaluate the number of pixels that were in both of the segmentation results obtained by the two image analysts (agreement) relative to the number of pixels that were not in both (disagreement). An overall agreement comparison was done by finding means and standard deviations of kappa statistics and the similarity measure found for each tissue type in the studies. The kappa statistics for white matter was the largest (0.80) followed by those of gray matter (0.68), partial volume (0.67), total lesion (0.66), and CSF (0.44). The similarity measure showed the same trend but it was always higher than kappa statistics. It was 0.85 for white matter, 0.77 for gray matter, 0.73 for partial volume, 0.72 for total lesion, and 0.47 for CSF.

Paper Details

Date Published: 24 June 1998
PDF: 11 pages
Proc. SPIE 3338, Medical Imaging 1998: Image Processing, (24 June 1998); doi: 10.1117/12.310931
Show Author Affiliations
Hamid Soltanian-Zadeh, Henry Ford Hospital and Univ. of Tehran (United States)
Joe P. Windham, Henry Ford Hospital (United States)
Lisa Scarpace, Henry Ford Hospital (United States)
Tanya Murnock, Henry Ford Hospital (United States)

Published in SPIE Proceedings Vol. 3338:
Medical Imaging 1998: Image Processing
Kenneth M. Hanson, Editor(s)

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