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Proceedings Paper

Measuring the accuracy and precision of quantitative coronary angiography using a digitally simulated test phantom
Author(s): Craig A. Morioka; James Stuart Whiting; Michelle T. LeFree
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Paper Abstract

Quantitative coronary angiography (QCA) diameter measurements have been used as an endpoint measurement in clinical studies involving therapies to reduce coronary atherosclerosis. The accuracy and precision of the QCA measure can affect the sample size and study conclusions of a clinical study. Measurements using x-ray test phantoms can underestimate the precision and accuracy of the actual arteries in clinical digital angiograms because they do not contain complex patient structures. Determining the clinical performance of QCA algorithms under clinical conditions is difficult because: (1) no gold standard test object exists in clinical images, (2) phantom images do not have any structured background noise. We purpose the use of computer simulated arteries as a replacement for traditional angiographic test phantoms to evaluate QCA algorithm performance.

Paper Details

Date Published: 24 June 1998
PDF: 9 pages
Proc. SPIE 3338, Medical Imaging 1998: Image Processing, (24 June 1998); doi: 10.1117/12.310855
Show Author Affiliations
Craig A. Morioka, Cedars-Sinai Medical Ctr. (United States)
James Stuart Whiting, Cedars-Sinai Medical Ctr. (United States)
Michelle T. LeFree, Quinton Imaging (United States)

Published in SPIE Proceedings Vol. 3338:
Medical Imaging 1998: Image Processing
Kenneth M. Hanson, Editor(s)

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