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Proceedings Paper

Corneal autofluorescence in presence of diabetic retinopathy
Author(s): Luigi Rovati; Franco Docchio; Claudio Azzolini; Jaap A. Van Best
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Paper Abstract

Recently corneal autofluorescence has been proposed as an ocular diagnostic tool for diabetic retinopathy. The method is based on the sensible increase of the natural fluorescence of corneal tissue within specific wavelength in presence of early stage of diabetic retinopathy. The main advantages of this method are that the corneal autofluorescence has been demonstrated to be not age-related and that the cornea is readily accessible to be investigated. In this study 47 insulin-dependent diabetes mellitus and 51 non-insulin- dependent diabetes mellitus patients aged 20 - 90 years have been considered. Patients were selected from the Eye Clinic of S. Raffaele Hospital. The modified Airlie House classification was used to grade the diabetic retinopathy. Corneal autofluorescence has been measured by using both a specifically designed instrument and the Fluorotron Master. Corneal autofluorescence mean value for each diabetic retinopathy measured by using both the instruments correlated with the retinopathy grade.

Paper Details

Date Published: 1 June 1998
PDF: 6 pages
Proc. SPIE 3246, Ophthalmic Technologies VIII, (1 June 1998); doi: 10.1117/12.309438
Show Author Affiliations
Luigi Rovati, Univ. degli Studi di Brescia (Italy)
Franco Docchio, Univ. degli Studi di Brescia (Italy)
Claudio Azzolini, San Raffaele Hospital/Univ. of Milan (Italy)
Jaap A. Van Best, Leiden Univ. Hospital (Netherlands)

Published in SPIE Proceedings Vol. 3246:
Ophthalmic Technologies VIII
Pascal O. Rol; Karen Margaret Joos; Fabrice Manns, Editor(s)

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