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Proceedings Paper

Relief of vasospasm by intravascular ultraviolet irradiation
Author(s): Kanji Nakai; Yuji Morimoto; Hirotaka Ito; Kimito Kominami; Hirotaka Matsuo; Tsunenori Arai; Makoto Kikuchi
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Paper Abstract

We investigated the photovasorelaxation with intravascular transluminal irradiation using in vivo model. A 2.5 Fr. catheter was inserted in the femoral artery of a rabbit under anesthesia. A 400 micrometers diameter quartz fiber was inserted through the catheter. The catheter was withdrawn from the distal end to the proximal end of the exposed femoral artery without laser irradiation in order to observe the mechanical dilation by the procedure. The femoral artery lumen was irradiated by a Helium-Cadmium(He-Cd) laser (wavelength; 325 nm) with 8 mW through the fiber during 30 s. We carried out that the laser irradiation produced vasorelaxation (185% on the average) compared with mechanical vasodilation (150% on the average) with angiography. The results suggest that intravascular transluminal irradiation with low-power UV laser might be applicable to the relief of acute arterial vasospasm.

Paper Details

Date Published: 13 May 1998
PDF: 4 pages
Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); doi: 10.1117/12.308205
Show Author Affiliations
Kanji Nakai, National Defense Medical College (Japan)
Yuji Morimoto, National Defense Medical College (Japan)
Hirotaka Ito, National Defense Medical College (Japan)
Kimito Kominami, National Defense Medical College (Japan)
Hirotaka Matsuo, National Defense Medical College (Japan)
Tsunenori Arai, National Defense Medical College (Japan)
Makoto Kikuchi, National Defense Medical College (Japan)

Published in SPIE Proceedings Vol. 3254:
Laser-Tissue Interaction IX
Steven L. Jacques; Jeff Lotz, Editor(s)

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