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Proceedings Paper

Lipometer subcutaneous adipose tissue topography (SAT-Top) reflects serum leptin levels varying in circadian rhythms
Author(s): Reinhard Moeller; Erwin Tafeit; Karl Sudi; Karoline Vrecko; Renate Horejsi; Helmut G. Hinghofer-Szalkay; Gilbert Reibnegger
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Paper Abstract

Recent advances in obesity research have shown that the product of the ob-gene named leptin is related to total body fast mass in humans. There is, however, a debate if leptin levels are pulsatile and linked to body fat distribution. In this study we therefore investigated the subcutaneous adipose tissue topography (SAT-Top) measured by means of the newly developed device Lipometer and leptin levels during a 24 hours beginning at 0715am ending the same time in the next day. Blood samples for measurement of leptin were taken every 3 hours in a male subject. Measurements of SAT-Top were performed at 15 body sites from neck to calf at the left and right body site at the same time interval. We observed an almost symmetrically reaction of the left and right body site with a maximum of the mean value of all body sites in the evening at 0715pm. There was a negative correlation between serum leptin levels and SAT-Top using the set of certain body sites (R2 equals 0.80, p equals 0.01). If these combination of body sites is inversed and set against serum leptin levels, both curves show almost identical shape and time dependence. We conclude that SAT-Top by means of Lipometer is changed in a short time and related to leptin levels in the investigated male subject.

Paper Details

Date Published: 13 May 1998
PDF: 6 pages
Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); doi: 10.1117/12.308196
Show Author Affiliations
Reinhard Moeller, Karl-Franzens-Univ. Graz (Austria)
Erwin Tafeit, Karl-Franzens-Univ. Graz (Austria)
Karl Sudi, Karl-Franzens-Univ. Graz (Austria)
Karoline Vrecko, Karl-Franzens-Univ. Graz (Austria)
Renate Horejsi, Karl-Franzens-Univ. Graz (Austria)
Helmut G. Hinghofer-Szalkay, Karl-Franzens-Univ. Graz (Austria)
Gilbert Reibnegger, Karl-Franzens-Univ. Graz (Austria)

Published in SPIE Proceedings Vol. 3254:
Laser-Tissue Interaction IX
Steven L. Jacques; Jeff Lotz, Editor(s)

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