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Proceedings Paper

Novel low-cost fiber optic colorimetric instrument to rapidly screen premalignant esophageal tissue
Author(s): Anupam K. Dattamajumdar; John A. Myers; Andrew H. Proctor; Douglas S. Levine; Patricia L. Blount; Brian J. Reid; Roy W. Martin
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Paper Abstract

A cost-efficient screening device is needed to detect patients who have Barrett's esophagus, a precursor to esophageal adenocarcinoma -- the most rapidly increasing cancer in the US. We have developed a prototype instrument based on colorimetric assessment of esophageal lumen. The system consists of a small diameter fiber-optic probe, interfacing electronics, a probe-head position sensor and a computer for display and analysis. The probe has a central plastic optical fiber through which white light is incident on the collapsed esophageal lumen via c conical mirror in the probe-head. A parabolic mirror in the probe-head focuses the reflected light is applied to a linear 520 X 3 RGB photo-diode array to generate proportional electrical signals. A position sensor tracks probe-head location as it is retracted, allowing generation of a 2D colormap of esophageal lumen. A color change from white to red indicates Barrett's esophagus. The system performed accurately in tests using models of esophageal lumen which simulate patterns observed in Barrett's esophagus.

Paper Details

Date Published: 1 May 1998
PDF: 10 pages
Proc. SPIE 3253, Biomedical Sensing and Imaging Technologies, (1 May 1998); doi: 10.1117/12.308050
Show Author Affiliations
Anupam K. Dattamajumdar, Univ. of Washington (United States)
John A. Myers, Univ. of Washington (United States)
Andrew H. Proctor, Univ. of Washington (United States)
Douglas S. Levine, Univ. of Washington (United States)
Patricia L. Blount, Univ. of Washington and Fred Hutchinson Cancer Research Ctr. (United States)
Brian J. Reid, Univ. of Washington and Fred Hutchinson Cancer Research Ctr. (United States)
Roy W. Martin, Univ. of Washington (United States)

Published in SPIE Proceedings Vol. 3253:
Biomedical Sensing and Imaging Technologies
Robert A. Lieberman; Tuan Vo-Dinh, Editor(s)

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