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Proceedings Paper

Virtual Human: a diagnostic tool for human studies and health effects in the 21st century
Author(s): Clay E. Easterly; Glenn O. Allgood; Keith Eckerman; Helmut E. Knee; Mike Maston; Greg McNeilly; John Munro; Nancy B. Munro; Ross Toedte; Blake Van Hoy; Richard C. Ward
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Paper Abstract

The virtual human will be a research/simulation environment having an integrated system of biophysical models, data, and advanced computational algorithms. It will have a Web-based interface for easy, rapid access from several points of entry. The virtual human will serve as a platform for national and international users from governments, academia and industry to investigate the widest range of human biological and physical response to stimuli, be they biological, chemical, or physical. This effort will go far beyond the modeling of anatomy to incorporate refined computational models of whole-body processes, using mechanical and electrical tissue properties, and biology from physiology to biochemical information. The platform will respond mechanistically to varied and potentially iterative stimuli that can be visualized multi- dimensionally. This effort is in the formative stage of a several-year process that will lead to a program that is of similar proportion to the human genome, but will be much more computationally intensive. The main purpose of this paper is to communicate our early ideas about the philosophic basis of the program, to identify some of the applications for which the virtual human would be used, to elicit comments, and to provide a basis to identify prospective collaborators.

Paper Details

Date Published: 1 May 1998
PDF: 5 pages
Proc. SPIE 3253, Biomedical Sensing and Imaging Technologies, (1 May 1998); doi: 10.1117/12.308024
Show Author Affiliations
Clay E. Easterly, Oak Ridge National Lab. (United States)
Glenn O. Allgood, Oak Ridge National Lab. (United States)
Keith Eckerman, Oak Ridge National Lab. (United States)
Helmut E. Knee, Oak Ridge National Lab. (United States)
Mike Maston, Oak Ridge National Lab. (United States)
Greg McNeilly, Oak Ridge National Lab. (United States)
John Munro, Oak Ridge National Lab. (United States)
Nancy B. Munro, Oak Ridge National Lab. (United States)
Ross Toedte, Oak Ridge National Lab. (United States)
Blake Van Hoy, Oak Ridge National Lab. (United States)
Richard C. Ward, Oak Ridge National Lab. (United States)


Published in SPIE Proceedings Vol. 3253:
Biomedical Sensing and Imaging Technologies
Robert A. Lieberman; Tuan Vo-Dinh, Editor(s)

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