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Proceedings Paper

Bioreceptor-conducting polymer multilayer assemblies for biosensing
Author(s): Lynne A. Samuelson; Shridhara Alva; Jayant Kumar; David L. Kaplan; Sukant K. Tripathy
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Paper Abstract

This research focuses on the organized integration of biological receptors and polymers into thin film architectures for biosensing applications. Layer-by-layer electrostatic adsorption was used for the first time to form alternating protein-conducting polymer multilayers. The light-harvesting, phycobiliproteins and the enzyme, alkaline phosphatase were the bioreceptors investigated and sulfonated polystyrene, poly(diallyl dimethyl ammonium chloride) and a new enzymatically polymerized, water soluble, polyaniline were the polymer counterions used for deposition. Spectroscopic characterization was used to determine both multilayer formation and biosensing function of the final bioreceptor-polymer assemblies. These techniques have proven to be simple, chemically mild, and versatile and are expected to find application in the fabrication of ultrathin films for biosensors, opto- electronic devices and biomedical applications.

Paper Details

Date Published: 16 April 1998
PDF: 12 pages
Proc. SPIE 3321, 1996 Symposium on Smart Materials, Structures, and MEMS, (16 April 1998); doi: 10.1117/12.305595
Show Author Affiliations
Lynne A. Samuelson, U.S. Army Natick Research, Development and Engineering Ctr. (United States)
Shridhara Alva, Univ. of Massachusetts/Lowell (United States)
Jayant Kumar, Univ. of Massachusetts/Lowell (United States)
David L. Kaplan, U.S. Army Natick Research, Development and Engineering Ctr. (United States)
Sukant K. Tripathy, Univ. of Massachusetts/Lowell (United States)

Published in SPIE Proceedings Vol. 3321:
1996 Symposium on Smart Materials, Structures, and MEMS
Vasu K. Aatre; Vijay K. Varadan; Vasundara V. Varadan, Editor(s)

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