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Proceedings Paper

Second harmonic and two-photon fluorescence histology of tissues
Author(s): Yici Guo; Feng Liu; Quan-Zhen Wang; Niclolay N. Zhadin; Peng Pei Ho; Howard E. Savage; D. Harris; Peter G. Sacks; Stimson P. Schantz; Robert R. Alfano
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Paper Abstract

Second harmonic and two photon fluorescence generated by focused 10 fs ultrashort laser pulses were used to image subsurface structures of highly scattering biological tissues. By scanning the focal point of the incident laser beam, 2D sectional images of the tissues subsurface structure properties, such as symmetry and molecular compositions are obtained.

Paper Details

Date Published: 16 April 1998
PDF: 3 pages
Proc. SPIE 3250, Optical Biopsy II, (16 April 1998); doi: 10.1117/12.305381
Show Author Affiliations
Yici Guo, CUNY/City College (United States)
Feng Liu, CUNY/City College (United States)
Quan-Zhen Wang, CUNY/City College (United States)
Niclolay N. Zhadin, CUNY/City College (United States)
Peng Pei Ho, CUNY/City College (United States)
Howard E. Savage, Memorial Sloan-Kettering Cancer Ctr. (United States)
D. Harris, Memorial Sloan-Kettering Cancer Ctr. (United States)
Peter G. Sacks, Memorial Sloan-Kettering Cancer Ctr. (United States)
Stimson P. Schantz, Memorial Sloan-Kettering Cancer Ctr. (United States)
Robert R. Alfano, CUNY/City College (United States)


Published in SPIE Proceedings Vol. 3250:
Optical Biopsy II
Robert R. Alfano, Editor(s)

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