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Proceedings Paper

Multiple protein sequence comparison by genetic algorithms
Author(s): Raquel Roche Gonzalez; Carmen Morato Izquierdo; Juan Seijas
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Paper Abstract

In the analysis of molecular evolution, it is very frequent to consider M sequences at a time, where M greater than 2. The simultaneous study of the relationships among M sequences is a large and difficult problem. This paper presents a new approach to multiple protein sequence comparison based on Genetic Algorithms, (G.A.). In particular, it is described an algorithm for finding the alignment of three protein sequences; besides, it can be easily changed for finding the alignment of more than three sequences or for other types of sequences. The G.A. was originally developed for only two sequences comparison [Morato96].

Paper Details

Date Published: 25 March 1998
PDF: 4 pages
Proc. SPIE 3390, Applications and Science of Computational Intelligence, (25 March 1998); doi: 10.1117/12.304857
Show Author Affiliations
Raquel Roche Gonzalez, Univ. Politecnica de Madrid (Spain)
Carmen Morato Izquierdo, Univ. Politecnica de Madrid (Spain)
Juan Seijas, Univ. Politecnica de Madrid (Spain)

Published in SPIE Proceedings Vol. 3390:
Applications and Science of Computational Intelligence
Steven K. Rogers; David B. Fogel; James C. Bezdek; Bruno Bosacchi, Editor(s)

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