Proceedings PaperFeasibility of interstitial thermotherapy with ultrasound waveguide applicator arrays
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We discuss potential of ultrasound waveguide applicator arrays for interstitial heating of brain tissue. First we describe specific absorption rate and show the importance of attenuation term at higher frequencies for cylindrical applicators. Ultrasound propagation characteristic to the applicator results in a shear component in the tissue. The component is significant over a small distance from the applicator. We obtain 3D temperature distribution using finite element analysis simulations for four-applicator array. The simulations show that the array is capable of heating the tissue to 56 degree(s)C. This high temperature leads to an undesired effect of heat toxicity in the adjacent tissue. The following simulations demonstrate how to optimize energy deposition, especially for asymmetries in boundary temperature. We investigate effects of effective thermal conductivity and antenna's length on the temperature pattern. We find that the array can be used for thermotherapy in clinically relevant volumes with the transducers operated at higher frequencies.