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Proceedings Paper

Intensity dependence of focused ultrasound lesion position
Author(s): Paul M. Meaney; Mark D. Cahill; Gail R. ter Haar
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Paper Abstract

Knowledge of the spatial distribution of intensity loss from an ultrasonic beam is critical to predicting lesion formation in focused ultrasound surgery. To date most models have used linear propagation models to predict the intensity profiles needed to compute the temporally varying temperature distributions. These can be used to compute thermal dose contours that can in turn be used to predict the extent of thermal damage. However, these simulations fail to adequately describe the abnormal lesion formation behavior observed for in vitro experiments in cases where the transducer drive levels are varied over a wide range. For these experiments, the extent of thermal damage has been observed to move significantly closer to the transducer with increasing transducer drive levels than would be predicted using linear propagation models. The simulations described herein, utilize the KZK (Khokhlov-Zabolotskaya-Kuznetsov) nonlinear propagation model with the parabolic approximation for highly focused ultrasound waves, to demonstrate that the positions of the peak intensity and the lesion do indeed move closer to the transducer. This illustrates that for accurate modeling of heating during FUS, nonlinear effects must be considered.

Paper Details

Date Published: 2 April 1998
PDF: 11 pages
Proc. SPIE 3249, Surgical Applications of Energy, (2 April 1998); doi: 10.1117/12.304348
Show Author Affiliations
Paul M. Meaney, Dartmouth College (United States)
Mark D. Cahill, St. Thomas' Hospital (United Kingdom)
Gail R. ter Haar, Royal Marsden Hospital (United Kingdom)

Published in SPIE Proceedings Vol. 3249:
Surgical Applications of Energy
Thomas P. Ryan, Editor(s)

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