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Proceedings Paper

Optical magnetophoretic analysis of blood cells and microparticles
Author(s): Svetlana B. Norina; Alexander N. Shalygin; Stanislav F. Rastopov
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Paper Abstract

The precise magnetophoretic measurements of magnetic susceptibility of red blood cells and sorbent microparticles fulfilled with the video-camera observation and light scattering detection were applied for the identification of the cellular free radical excess under oxidative stress, paramagnetic ions changes and the immunospecific binding detection. The fast and sensitive assay allows to determine weak paramagnetic or diamagnetic shifts relatively surrounding solution connected with hematological and metabolic cellular disorders, external chemical influences by ions and organic molecules additions in range 10-4 - 10-6 M. The autoregistration of magnetophoresis facilitated the analysis of the functional states of cells and the macromolecular binding detection.

Paper Details

Date Published: 1 January 1998
PDF: 6 pages
Proc. SPIE 3199, Biomedical Systems and Technologies II, (1 January 1998); doi: 10.1117/12.301129
Show Author Affiliations
Svetlana B. Norina, Moscow State Univ. (Russia)
Alexander N. Shalygin, Moscow State Univ. (Russia)
Stanislav F. Rastopov, General Physics Institute (Russia)


Published in SPIE Proceedings Vol. 3199:
Biomedical Systems and Technologies II
Francesco Baldini; Nathan I. Croitoru; Mark Russell Dickinson; Martin Frenz; Mitsunobu Miyagi; Riccardo Pratesi; Stefan Seeger, Editor(s)

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