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Proceedings Paper

2D CCD imaging in oblique incidence for noninvasive measurement of biological tissues optical coefficients
Author(s): Laure Voisin; Loic Blanchot; D. Kalinowski; Jean A. Virmont; Guy Ledanois; Herve Saint-Jalmes
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Paper Abstract

The measurement of absorption and scattering optical parameters (mu) a and (mu) 's is difficult in vivo. We developed a new method for non invasive measurement of these coefficients. It is based on existing steady state reflectance methods but it reduces the sensitivity to noise with an integration method. It also decreases the dependence on the sample roughness and on the angular position of the source regarding the sample. The image is circularly integrated versus the radius from the maximum to the nearest side. The integral reflectance is then fitted with a theoretical formula using 2 point sources model. We validate the method on simulation images and on calibrated Latex beads suspensions used as scattering phantoms. The integral reflectance method has then been applied to the measurements of (mu) a and (mu) 's coefficients of the human skin in vivo. We have obtained a good reproducibility of the results.

Paper Details

Date Published: 1 January 1998
PDF: 6 pages
Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); doi: 10.1117/12.301066
Show Author Affiliations
Laure Voisin, Univ. Paris XII (France)
Loic Blanchot, Univ. Paris XII (France)
D. Kalinowski, Univ. Paris XII (France)
Jean A. Virmont, Ecole Polytechnique (France)
Guy Ledanois, Ecole Polytechnique (France)
Herve Saint-Jalmes, Univ. Paris XII (France)

Published in SPIE Proceedings Vol. 3194:
Photon Propagation in Tissues III
David A. Benaron M.D.; Britton Chance; Marco Ferrari, Editor(s)

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