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Proceedings Paper

Accurate NIRS measurement of muscle oxygenation by correcting the influence of a subcutaneous fat layer
Author(s): Katsuyuki Yamamoto; Masatsugu Niwayama; Ling Lin; Toshikazu Shiga; Nobuki Kudo; Makoto Takahashi
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Paper Abstract

Although the inhomogeneity of tissue structure affects the sensitivity of tissue oxygenation measurement by reflectance near-infrared spectroscopy, few analyses of this effect have been reported. In this study, the influence of a subcutaneous fat layer on muscle oxygenation measurement was investigated by Monte Carlo simulation and experimental studies. In the experiments, measurement sensitivity was examined by measuring the falling rate of oxygenation in occlusion tests on the forearm using a tissue oxygen monitor. The fat layer thickness was measured by ultrasonography. Results of the simulation and occlusion tests clearly showed that the presence of a fat layer greatly decreases the measurement sensitivity and increases the light intensity at the detector. The correction factors of sensitivity were obtained from this relationship and were successfully validated by experiments on 12 subjects whose fat layer thickness ranged from 3.5 to 8 mm.

Paper Details

Date Published: 1 January 1998
PDF: 8 pages
Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); doi: 10.1117/12.301049
Show Author Affiliations
Katsuyuki Yamamoto, Hokkaido Univ. (Japan)
Masatsugu Niwayama, Hokkaido Univ. (Japan)
Ling Lin, Hokkaido Univ. (Japan)
Toshikazu Shiga, Omron Institute of Life Science Co., Ltd. (Japan)
Nobuki Kudo, Hokkaido Univ. (Japan)
Makoto Takahashi, Hokkaido Univ. (Japan)

Published in SPIE Proceedings Vol. 3194:
Photon Propagation in Tissues III
David A. Benaron; Britton Chance; Marco Ferrari, Editor(s)

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