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Proceedings Paper

Automated classification of tissue by type using real-time spectroscopy
Author(s): David A. Benaron; Wai-Fung Cheong; Joshua L. Duckworth; Kenneth Noles; Camran Nezhat; Daniel Seidman; Susan R. Hintz; Carl J. Levinson; Aileen L. Murphy; John W. Price; Frank W.H. Liu; David K. Stevenson; Eben L. Kermit
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Paper Abstract

Each tissue type has a unique spectral signature (e.g. liver looks distinct from bowel due to differences in both absorbance and in the way the tissue scatters light). While differentiation between normal tissues and tumors is not trivial, automated discrimination among normal tissue types (e.g. nerve, artery, vein, muscle) is feasible and clinically important, as many medical errors in medicine involve the misidentification of normal tissues. In this study, we have found that spectroscopic differentiation of tissues can be successfully applied to tissue samples (kidney and uterus) and model systems (fruit). Such optical techniques may usher in use of optical tissue diagnosis, leading to automated and portable diagnostic devices which can identify tissues, and guide use of medical instruments, such as during ablation or biopsy.

Paper Details

Date Published: 29 December 1997
PDF: 9 pages
Proc. SPIE 3197, Optical Biopsies and Microscopic Techniques II, (29 December 1997); doi: 10.1117/12.297957
Show Author Affiliations
David A. Benaron, Stanford Univ. School of Medicine and Stanford Univ. (United States)
Wai-Fung Cheong, Stanford Univ. School of Medicine and Spectros Corp. (United States)
Joshua L. Duckworth, Spectros Corp. (United States)
Kenneth Noles, Stanford Univ. School of Medicine (United States)
Camran Nezhat, Stanford Univ. School of Medicine (United States)
Daniel Seidman, Stanford Univ. School of Medicine (United States)
Susan R. Hintz, Stanford Univ. School of Medicine (United States)
Carl J. Levinson, Stanford Univ. School of Medicine (United States)
Aileen L. Murphy, Spectros Corp. (United States)
John W. Price, Spectros Corp. (United States)
Frank W.H. Liu, Spectros Corp. (United States)
David K. Stevenson, Stanford Univ. School of Medicine (United States)
Eben L. Kermit, Spectros Corp. (United States)


Published in SPIE Proceedings Vol. 3197:
Optical Biopsies and Microscopic Techniques II
Irving J. Bigio; Herbert Schneckenburger; Jan Slavik; Katarina Svanberg; Pierre M. Viallet, Editor(s)

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