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Proceedings Paper

Simulation studies of vapor bubble generation by short-pulse lasers
Author(s): Peter A. Amendt; Richard A. London; Moshe Strauss; Michael E. Glinsky; Duncan J. Maitland; Peter M. Celliers; Steven R. Visuri; David S. Bailey; David A. Young; Darwin Ho; Charles P. Lin; Michael W. Kelly
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Paper Abstract

Formation of vapor bubbles is characteristic of many applications of short-pulse lasers in medicine. An understanding of the dynamics of vapor bubble generation is useful for developing and optimizing laser-based medical therapies. To this end, experiments in vapor bubble generation with laser light deposited in an aqueous dye solution near a fiber-optic tip have been performed. Numerical hydrodynamic simulations have been developed to understand and extrapolate results from these experiments. Comparison of two-dimensional simulations with the experiment shows excellent agreement in tracking the bubble evolution. Another regime of vapor bubble generation is short-pulse laser interactions with melanosomes. Strong shock generation and vapor bubble generation are common physical features of this interaction. A novel effect of discrete absorption by melanin granules within a melanosome is studied as a possible role in previously reported high Mach number shocks [Lin and Kelly, SPIE 2391, 294 (1995)].

Paper Details

Date Published: 14 January 1998
PDF: 14 pages
Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); doi: 10.1117/12.297909
Show Author Affiliations
Peter A. Amendt, Lawrence Livermore National Lab. (United States)
Richard A. London, Lawrence Livermore National Lab. (United States)
Moshe Strauss, Nuclear Research Ctr. (Israel)
Michael E. Glinsky, Lawrence Livermore National Lab. (United States)
Duncan J. Maitland, Lawrence Livermore National Lab. (United States)
Peter M. Celliers, Lawrence Livermore National Lab. (United States)
Steven R. Visuri, Lawrence Livermore National Lab. (United States)
David S. Bailey, Lawrence Livermore National Lab. (United States)
David A. Young, Lawrence Livermore National Lab. (United States)
Darwin Ho, Lawrence Livermore National Lab. (United States)
Charles P. Lin, Massachusetts General Hospital/Harvard Medical School (United States)
Michael W. Kelly, Massachusetts General Hospital/Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 3195:
Laser-Tissue Interaction, Tissue Optics, and Laser Welding III
Guy P. Delacretaz; Guilhem Godlewski; Roberto Pini; Rudolf W. Steiner; Lars Othar Svaasand, Editor(s)

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