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Proceedings Paper

Comparative histologic study of alterations in rat skeletal muscles due to carbon dioxide laser with varying power but constant energy
Author(s): Ester Maria Danielli Nicola; Adriana Azevedo Coutinho; Konradin Metze; Jorge Humberto Nicola
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Paper Abstract

The aim of our study was to compare biolgic effects such as tissue damage and regeneration in rat skeletal muscle after CO2 laser application with pulses of constant energy density, but with varying power and exposure time. We used three different laser conditions: 20 W by 0.5 s, 10 W by 1.0 s and 5.0 W by 2.0 s, all having the same energy density (10 joules in a constant area). The animals were sacrificed immediately after laser application, and after 1, 4, 7, 15 and 21 days. Tissue damage produced by the CO2 laser with high power provokes more profound craters with less tissue damage at the margins. As shown by lesser tissue carbonization, fewer foreign body giant cell granulomas and less tissue fibrosis and, on the other hand, an accelerated regeneration of muscle tissue.

Paper Details

Date Published: 14 January 1998
PDF: 8 pages
Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); doi: 10.1117/12.297890
Show Author Affiliations
Ester Maria Danielli Nicola, State Univ. of Campinas (Brazil)
Adriana Azevedo Coutinho, State Univ. of Campinas (Brazil)
Konradin Metze, State Univ. of Campinas (Brazil)
Jorge Humberto Nicola, Institute of Microelectronics/CTI (Brazil)

Published in SPIE Proceedings Vol. 3195:
Laser-Tissue Interaction, Tissue Optics, and Laser Welding III
Guy P. Delacretaz; Guilhem Godlewski; Roberto Pini; Rudolf W. Steiner; Lars Othar Svaasand, Editor(s)

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