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Proceedings Paper

Kinetics of zona pellucida thermodissolution in mouse zygotes
Author(s): Laurent Descloux; Sohi Rastegar; Guy P. Delacretaz; Artha J. Hollis; Klaus Rink
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Paper Abstract

Zona Pellucida (ZP), the outer protective layer of mammalian eggs, is composed of glycoproteins that can be dissolved by temperature elevation. The kinetics of this thermo-dissolution process can play an important role in understanding the mechanism of photothermolysis by a laser. While a temperature of around 70 degrees Celsius has been previously reported as the critical dissolution temperature for the ZP, we found in this study that dissolution temperature has a wider range and depends on duration of exposure which suggests a kinetic rate process. In this paper we report the results of our measurements at different prescribed temperature elevations and subsequent calculations of the kinetics constants using an Arrhenius model.

Paper Details

Date Published: 14 January 1998
PDF: 6 pages
Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); doi: 10.1117/12.297888
Show Author Affiliations
Laurent Descloux, Ecole Polytechnique Federale de Lausanne (Switzerland)
Sohi Rastegar, Texas A&M Univ. (United States)
Guy P. Delacretaz, Ecole Polytechnique Federale de Lausanne (Switzerland)
Artha J. Hollis, Texas A&M Univ. (United States)
Klaus Rink, Medical Technologies Montreux SA (Switzerland)

Published in SPIE Proceedings Vol. 3195:
Laser-Tissue Interaction, Tissue Optics, and Laser Welding III
Guy P. Delacretaz; Guilhem Godlewski M.D.; Roberto Pini; Rudolf W. Steiner; Lars Othar Svaasand, Editor(s)

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