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Proceedings Paper

Development of a probe for use with the Paterson lamp in photodynamic therapy (PDT) of the esophagus and colorectum
Author(s): Joseph V. E. Roche; Colin Whitehurst; Peter Watt; James V. Moore; Neville Krasner
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Paper Abstract

The Paterson lamp is a convenient, low cost, portable, alternative light source to lasers for PDT. A multi- wavelength capability enables the clinician to vary the photosensitizer used. The Paterson lamp has been applied in the field of dermatology using a liquid light guide with distal optics for surface application. We now describe distal optics suitable for use with this light guide for intraluminal applications in the oesophagus and colorectum. The geometry of the site (oesophagus and colorectum) requires distal optics such as a cylindrical diffuser or a side fire diffuser. We have designed new cylindrical probes that diffuse light radially from the guide axis (cylindrical diffusion). The tips have a frosted glass surface that scatters and effectively couples light radially into the tissue. An acrylic spacer is placed over the diffuser to position the tissue at a constant diameter from the probe. This is held in position by a silicone sheath placed over the distal one meter. For use in the oesophagus, a channel, to facilitate intubation over a guide wire, is included. The diameter of the entire probe is 8.4 mm and the power output can be adjusted from 0 - 500 mW.

Paper Details

Date Published: 22 December 1997
PDF: 6 pages
Proc. SPIE 3192, Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry, and Endoscopy, (22 December 1997); doi: 10.1117/12.297851
Show Author Affiliations
Joseph V. E. Roche, Fazakerley Hospital (United Kingdom)
Colin Whitehurst, Paterson Institute for Cancer Research (United Kingdom)
Peter Watt, Fazakerley Hospital (United Kingdom)
James V. Moore, Paterson Institute for Cancer Research (United Kingdom)
Neville Krasner, Fazakerley Hospital (United Kingdom)

Published in SPIE Proceedings Vol. 3192:
Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry, and Endoscopy
Gregory B. Altshuler; Reginald Birngruber; Marco Dal Fante; Raimund Hibst; Herbert Hoenigsmann; Neville Krasner; Frederic Laffitte, Editor(s)

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