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Proceedings Paper

Quantitative studies on photodynamic effects
Author(s): Tamas Kriska; Judit Jakus; Agnes Keszler; Laszlo Korecz; Dezso Gal
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Paper Abstract

According to our hypothesis the interactions of triplet photosensitizer molecules with doublet free radicals generated in vivo (native free radicals) play an important role in the overall photodynamic effect (MTO mechanism). In order to support this mechanism, experiments have been performed recently in vivo, in vitro and in chemical model systems. The precondition of such studies, however, is the measurement of the kinetic parameters of various native free radicals generated in the systems investigated. Experimental results and their kinetic evaluation indicate that the triplet-doublet interactions may actually take place in the overall processes under study.

Paper Details

Date Published: 29 December 1997
PDF: 11 pages
Proc. SPIE 3191, Photochemotherapy: Photodynamic Therapy and Other Modalities III, (29 December 1997); doi: 10.1117/12.297817
Show Author Affiliations
Tamas Kriska, Central Research Institute for Chemistry (Hungary)
Judit Jakus, Central Research Institute for Chemistry (Hungary)
Agnes Keszler, Central Research Institute for Chemistry (Hungary)
Laszlo Korecz, Central Research Institute for Chemistry (Hungary)
Dezso Gal, Central Research Institute for Chemistry (Hungary)


Published in SPIE Proceedings Vol. 3191:
Photochemotherapy: Photodynamic Therapy and Other Modalities III
Kristian Berg; Benjamin Ehrenberg; Zvi Malik; Johan Moan; Abraham Katzir, Editor(s)

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