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Proceedings Paper

Localization of porphyrine amino acid derivatives in superficial tumors using laser-induced fluorescence
Author(s): Miroslaw Kwasny; Zygmunt Mierczyk; Andrzej Gietka; Alfreda Graczyk; Janusz Domaniecki
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Paper Abstract

The results of examinations of accumulation of bis-1(I- alanylo-N)-ethylo-deuteroprotoporfiryne (Ala-PP) in healthy tissues and superficial tumors of 10 patients are presented. Fluorescence imaging was carried out by means of a CCD camera, coupled with an image amplifier. As an excitation source a titanium laser was used. Contrary to healthy tissues, the tumor ones are characterized by the slight decrease in Ala-PP concentration during several days after injection of preparation what enables initial determination of a tissue character and next application of a selective therapeutic irradiation.

Paper Details

Date Published: 23 October 1997
PDF: 10 pages
Proc. SPIE 3188, Laser Technology V: Applications in Medicine and Ecology, (23 October 1997); doi: 10.1117/12.292852
Show Author Affiliations
Miroslaw Kwasny, Military Univ. of Technology (Poland)
Zygmunt Mierczyk, Military Univ. of Technology (Poland)
Andrzej Gietka, Military Univ. of Technology (Poland)
Alfreda Graczyk, Military Univ. of Technology (Poland)
Janusz Domaniecki, Military Medical Academy (Poland)

Published in SPIE Proceedings Vol. 3188:
Laser Technology V: Applications in Medicine and Ecology
Wieslaw Wolinski; Alfreda Graczyk, Editor(s)

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