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Proceedings Paper

Deformable anatomical templates for brachytherapy treatment planning in radiotherapy of cervical cancer
Author(s): Gary E. Christensen; Jeffrey F. Williamson; K. S. C. Chao; Michael I. Miller; F. B. So; Michael W. Vannier M.D.
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Paper Abstract

This paper describes a new method to register serial, volumetric x-ray computed tomography (CT) data sets for tracking soft-tissue deformation caused by insertion of intracavity brachytherapy applicators to treat cervical cancer. 3D CT scans collected from the same patient with and without a brachytherapy applicator are registered to aid in computation of the radiation dose to tumor and normal tissue. The 3D CT image volume of pelvic anatomy with the applicator. Initial registration is accomplished by rigid alignment of the pelvic bones and non-rigid alignment of gray scale CT data and hand segmentations of the vagina, cervix, bladder, and rectum. A viscous fluid transformation model is used for non-rigid registration to allow for local, non-linear registration of the vagina, cervix, bladder, and rectum without disturbing the rigid registration of the bony pelvis and adjacent structures. Results are presented in which two 3D CT data sets of the same patient - imaged with and without a brachytherapy applicator - are registered.

Paper Details

Date Published: 20 October 1997
PDF: 8 pages
Proc. SPIE 3168, Vision Geometry VI, (20 October 1997); doi: 10.1117/12.292779
Show Author Affiliations
Gary E. Christensen, Univ. of Iowa (United States)
Jeffrey F. Williamson, Washington Univ. (United States)
K. S. C. Chao, Washington Univ. (United States)
Michael I. Miller, Washington Univ. (United States)
F. B. So, Washington Univ. (United States)
Michael W. Vannier M.D., Univ. of Iowa (United States)

Published in SPIE Proceedings Vol. 3168:
Vision Geometry VI
Robert A. Melter; Angela Y. Wu; Longin Jan Latecki, Editor(s)

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