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Proceedings Paper

Light scattering from cells and organelles of arbitrary shape
Author(s): Andrew K. Dunn; Rebecca R. Richards-Kortum
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Paper Abstract

Using the finite-difference time-domain technique (FDTD), the scattering patterns from cells and organelles of arbitrary shape can be computed. With this method Maxwell's curl equations are discretized in space and time and the electric and magnetic fields are computed at all points within and around the cell. The cell is constructed as a dielectric object and the far-field scattering pattern, containing both amplitude and direction information is computed. Results are presented for three-dimensional cells containing different combinations of organelles, such as nucleus, cytoplasm, and mitochondria, to assess the effect of each on the scattering pattern. The computed scattering patterns indicate that small organelles such as mitochondria play an important role in scattering from cells and variations in the refractive index of the nucleus also affect the scattering characteristics.

Paper Details

Date Published: 18 August 1997
PDF: 8 pages
Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); doi: 10.1117/12.280290
Show Author Affiliations
Andrew K. Dunn, Univ. of Texas at Austin (United States)
Rebecca R. Richards-Kortum, Univ. of Texas at Austin (United States)


Published in SPIE Proceedings Vol. 2979:
Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II
Britton Chance; Robert R. Alfano, Editor(s)

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