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Proceedings Paper

Effect of spatially distributed light sources on the frequency-domain solution to the diffusion equation
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Paper Abstract

We have investigated the accuracy of the frequency-domain, diffusion equation Green's function in modeling optical signals in turbid media. Our optical measurements were conducted in strongly scattering media having absorption coefficients in the range 0.035 - 0.14 cm-1 and reduced scattering coefficients in the range 5 - 22 cm-1. The optical signal was both delivered to and collected from the sample by means of optical fibers. We have verified that the r-independent factor in the Green's function does not agree with the experimental data. This discrepancy shows that the photons launched in the medium by an optical fiber cannot be modeled by a point source located at a fixed position. These results have no influence on multi-distance measurement protocols (which only employ the r-dependent part of the solution), while they must be considered when calibration measurements on a known sample are performed.

Paper Details

Date Published: 18 August 1997
PDF: 6 pages
Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); doi: 10.1117/12.280285
Show Author Affiliations
Sergio Fantini, Univ. of Illinois/Urbana-Champaign (United States)
Maria-Angela Franceschini, Univ. of Illinois/Urbana-Champaign (United States)
Enrico Gratton, Univ. of Illinois/Urbana-Champaign (United States)


Published in SPIE Proceedings Vol. 2979:
Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II
Britton Chance; Robert R. Alfano, Editor(s)

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