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Proceedings Paper

Diffusing temporal light correlation for burn diagnosis
Author(s): David A. Boas; Goro Nishimura; Arjun G. Yodh
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Paper Abstract

The non-invasive determination of the depth of severe burns is an important problem whose solution would offer medical practitioners a valuable tool for diagnosing and treating severe burns. Burned tissue is essentially a turbid medium with spatial varying dynamics: light is multiply scattered by the tissue and layers of burned tissue are distinguished by the degree of blood flow. The dynamical properties of turbid media can be probed by monitoring the temporal fluctuations of scattered light speckles. Information on a system's dynamics is obtained from the temporal autocorrelation function of these intensity fluctuations. We have recently shown that the correlation diffusion equation (CDE) accurately predicts the temporal correlation function for turbid systems with spatially varying dynamics and that the dynamical properties of such systems can be imaged using standard reconstruction algorithms. In this contribution, we demonstrate the sensitivity of temporal field correlation measurements to variations of 100 micrometers in burn thickness and the potential applicability of the CDE for quantitation of burn thickness. Results are presented from burn phantoms and pig models. The combination of diffusing temporal light correlation with diffuse reflectometry for enhanced burn diagnosis is investigated.

Paper Details

Date Published: 18 August 1997
PDF: 10 pages
Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); doi: 10.1117/12.280281
Show Author Affiliations
David A. Boas, Tufts Univ. (United States)
Goro Nishimura, Hokkaido Univ. (Japan)
Arjun G. Yodh, Univ. of Pennsylvania (United States)

Published in SPIE Proceedings Vol. 2979:
Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II
Britton Chance; Robert R. Alfano, Editor(s)

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